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Your medical. Crosschecked.

Sleep

Zaleplon and your FAA medical

Prescription sleep aid
Other names: Sonata

FAA guidance

Do not fly while taking it.

Wait

12 hours

after the last dose

Source: FAA, Sleep Aids. FAA date 7 May 2025. Checked by Crosscheck 11 November 2026

The FAA sets a 12-hour minimum wait after zaleplon before pilot duties.

Track your medications
More detail: zaleplonThe rest of Crosscheck's reading, in plain wordsOpen

It says occasional or limited use of sleep aids, such as for circadian rhythm disruption in commercial air operations, is allowable for pilots, and daily or nightly use of sleep aids is not allowed regardless of the underlying cause or reason.

  • 12 hours after the last dose: no flying

FAA rule for sleep medication: The FAA puts all currently available sleep aids on its Do Not Fly list, prescription and over-the-counter alike, and if the pilot uses one routinely, the FAA's table says the examiner should defer. Its sleep aids page says occasional or limited use of sleep aids, such as for circadian rhythm disruption in commercial air operations, is allowable for pilots, and daily or nightly use of sleep aids is not allowed regardless of the underlying cause or reason. It also says medical conditions that chronically interfere with sleep are disqualifying regardless of whether a sleep aid is used or not. FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times

Show the FAA's words: zaleplonThe official FAA wording: one passage, each with its document and dateOpen
FAA, Sleep Aids · FAA date 7 May 2025
Required minimum waiting time after last dose before resuming pilot duties
Because of the potential for impairment, we require a minimum wait time between the last dose of a sleep aid and performing pilot duties.
The minimum required wait time after the last dose of a sleep aid is 5-times the maximum elimination half life.
Sonata, zaleplon, 12 hours.
Occasional or limited use of sleep aids, such as for circadian rhythm disruption in commercial air operations, is allowable for pilots. Daily/nightly use of sleep aids is not allowed regardless of the underlying cause or reason.
Sources and dates: zaleplonOne FAA document, with the FAA's date and when Crosscheck checked itOpen
  • Sleep Aids

    FAA date 7 May 2025 · Checked by Crosscheck 11 November 2026 · Web page

Questions pilots ask

Each answer is built from the FAA guidance on this page. Its sources and dates are in the page.

What does the FAA say about zaleplon for pilots?

FAA guidance: Do not fly while taking it. The FAA sets a 12-hour minimum wait after zaleplon before pilot duties. It says occasional or limited use of sleep aids, such as for circadian rhythm disruption in commercial air operations, is allowable for pilots, and daily or nightly use of sleep aids is not allowed regardless of the underlying cause or reason. Crosscheck does not predict the FAA's decision.

How long is the FAA's wait for zaleplon?

12 hours after the last dose.

Related pages

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.